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CASE REPORT
Year : 2019  |  Volume : 8  |  Issue : 13  |  Page : 35-37

Alobar holoprosencephaly in one of twin neonates


Department of Radiology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria

Correspondence Address:
Bukunmi Michael Idowu
Department of Radiology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/nnjcr.nnjcr_1_18

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Holoprosencephaly (HPE) is a congenital structural anomaly of the forebrain which is often diagnosed prenatally, usually in singleton pregnancies. This is a case of alobar HPE affecting one of 19-day-old twin neonates which was only detected postnatally. The other twin was unaffected. The anomaly was not diagnosed in utero because a prenatal sonogram was not performed. This case is presented to reemphasize the need for thorough routine prenatal/obstetrics sonography. After birth, transfontanelle ultrasonography is a useful imaging modality for diagnosing this debilitating cerebral structural anomaly, but definitive classification requires cross-sectional brain imaging with computed tomography or magnetic resonance imaging.


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